Is DMHA 2-Aminoisoheptane a worthy successor to geramine?

Geramine , also known as 1.3-dimethylamylamine or methylhexanamine, is a strong stimulating substance that has been driving the most powerful pre-workouts and burners for several years. The substance was also available for purchase in the form of a mono-preparation, which was popular among people who like to mix their own stacks. Unfortunately, legal restrictions quickly covered geramine with their tentacles, causing it to regularly disappear from the market, and manufacturers had to combine with its worthy successor. In this way, DMHA 2-Aminoisoheptane appeared on the market, which was hailed as a worthy successor to geramine.

Is this reflected in the action?
Does DMHA worthily replace DMAA?
Let’s take a closer look.

What is DMHA 2-Aminoisoheptane?

2-Aminoisoheptane belongs to the group of stimulants with strong stimulating, nootropic and thermogenic effects. DMHA appeared in the USA, in supplements, already around 2016. In Europe it became popular at the beginning of 2019, where geramine was officially banned. DMHA is also known in the form of an extract from the Juglans Regia plant, which is rich in alkaloids. In fact, under the name 2-Aminoisoheptane there are two substances: 2-amino-6-methylheptane and 2-amino-5-methylheptane, but in supplementation -amino-6-methylheptane is used. Other names found in blends are Octodrine, 1,5-dimethylhexylamine. It is from the latter that the abbreviation DMHA came from, which has been adopted by the media and is written in the names of supplements.

Action of 2-Aminoisoheptane

DMHA, like DMAA and DMBA (AMP Citrate), are classified as sympathomimetic stimulants [1]. Their main action will be to stimulate the release of dopamine and norepinephrine, which work by increasing euphoria and alertness. After using the supplement, we are stimulated and accompanied by a better mood. We are more action-oriented, positively wound up. DMHA crosses the blood-brain barrier well, which causes a strong response from the nervous system. Causes strong focus and euphoria.

Another action that intensifies the stimulation of the nervous system is the significant affinity of DMHA for catecholamines. Reducing the reuptake of epinephrine and norepinephrine translates into their greater presence in the body [2]. In addition, DMHA has a decongestant effect on the nasal mucosa, giving the typical feeling of a “cold nose” after using the supplement. This effect was used to alleviate the effects of upper respiratory tract infections, which facilitated m.in breathing. There are also some indications that DMHA can cause bronchodilation, which will directly translate into increased efficiency of the body.

Above, we focused mainly on the description of the activity supporting effort, and what about the use of DMHA during mental work or learning?
As mentioned above in the text, the stimulant effect is not as aggressive as in the case of DMAA. This means that DMHA will also work well during mental work and learning. What’s more, stimulating dopamine ejection may contribute to increasing episodic memory [3]. Dopamine has also been shown to allow you to stay in action longer. This means that people with high dopamine levels will be more focused and engaged on the task at hand. This behavior can be useful both during work, study and training.

Finally, it is necessary to mention the action of… pro-health.

So! DMHA also has a pro-health effect, such as support in the treatment of ringworm of the digestive system, or antibacterial effect [4]. Unfortunately, this also has its bad sides. If the substance turns out to be very effective. Will do really well in the treatment of the above-mentioned ailments. Then there is a very high probability that it will be used for treatment and registered as a drug. This will mean that supplement manufacturers will again get a ban… This time for the use of DMHA in their products. Will this happen? Time will tell. For now, we can enjoy the addition without major restrictions.

DMHA vs DMAA?

It is assumed that the potency of DMHA is 80% comparable to the strength of DMAA. Of course, these types of comparisons are only subjective feelings of many users of pre-workouts and they may result from the combination of various active substances. However, in this comparison there is a certain dependence, which we also confirm. Of course, this is not a 1:1 comparison of the amount of the active substance.

Approximately 150 mg of DMHA corresponds to a potency of 50 mg of DMAA. If until now DMAA in a dose of 30-50 mg worked well for you, so supplements with an amount of 100-150 mg of DMHA should give an 80% similar impression. Sounds pretty good!

The difference in the action of DMAA and DMHA is also the less aggressive effect of DMHA. We mean that DMHA stimulates, strongly stimulates activity, but does not cause distraction, and has a stronger nootropic effect. DMHA will allow us to focus on reading and learning in such a way that we will remember a lot of it. In the case of DMAA, psychomotor agitation is so strong that, even when you sit down to books, you will hardly remember anything about it.

What to combine DMHA with?

DMHA itself is already working pretty well. Of course, our experience shows that about 150-200 mg will already give us an interesting level of arousal. Is able to last for 3-4 hours, depending on the reaction of the individual body. A good complement here is caffeine in a dose of 200-300 mg. Is always a good foundation when it comes to the action of stronger stimulants. Caffeine will allow us to go a little milder from the center, we will not feel clearly that it has stopped working. Advanced people who like strong mixtures can successfully add alpha yohimbine in the amount of 1 mg. To sum up, a mixture of 150 DMHA, 200 mg of caffeine and 1 mg of alpha yohimbine. Will be a solution that should satisfy anyone who likes strong arousal during training.

In what supplements will we get DMHA?

In our opinion, the 5 most interesting supplements that currently contain a solid dose of DMHA are:

1. Apollon Nutrition Assassin, which contains an extract from the Juglans Regia plant, which is a source of DMHA.
   
2. Submission Science Roky KO Round 2, containing 2-Aminoisoheptane,
   
3. Hammer Labz Monster Strengh with 2-Aminoisoheptane in the composition,
   
4. Centurion Labz Rage with 2-amino-5-methylheptane in the composition,
   
5. Gold Star Triple X with 2-Aminoisoheptane in the lineup.
   

You can find the best DMHA supplements on BodyShock.PRO

Sources:
https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/dta.1852
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC2593006
https://www.nature.com/articles/nrn1406
https://ann-clinmicrob.biomedcentral.com/articles/10.1186/s12941-015-0090-4